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乙型流感病毒核酸檢測試劑盒(PCR方法)
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【公司名稱】 廣州健侖生物科技有限公司
【市場部】 楊永漢
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【騰訊 】 2042552662
【公司地址】 廣州清華科技園創(chuàng)新基地番禺石樓鎮(zhèn)創(chuàng)啟路63號(hào)二期2幢101-103室
對于擬南芥而言,陽光誘導(dǎo)的信號(hào)傳導(dǎo)過程包括,一個(gè)活化的感光分子(光敏色素)結(jié)合到轉(zhuǎn)錄因子PIF上。這種結(jié)合會(huì)摧毀PIF,關(guān)閉它的目標(biāo)基因。然而研究人員發(fā)現(xiàn),光敏色素在使PIF摧毀的同時(shí),也判下了自己的死刑,這一指令被立即執(zhí)行導(dǎo)致信號(hào)強(qiáng)度減弱。
“理解植物對光的應(yīng)答動(dòng)態(tài),解析其背后的分子機(jī)制,有助于我們對作物進(jìn)行基因工程改造,使其能夠更好的適應(yīng)環(huán)境波動(dòng),”文章的共同作者,卡內(nèi)基的王志勇教授說。
研究人員用相互確保摧毀MAD(mutually assured destruction)來形容這種同歸于盡的信號(hào)減弱機(jī)制(MAD本是一種相互威懾的冷戰(zhàn)策略)。自然界通過這種機(jī)制為關(guān)鍵性的功能保駕護(hù)航,而它將為人們提供廣泛的啟示(從農(nóng)業(yè)到癌癥研究)。
對研究干細(xì)胞療效的醫(yī)學(xué)專家來說,zui大的挑戰(zhàn)在于,移植物或細(xì)胞常常被主體排斥,這就使一些有潛力挽救生命的療法進(jìn)展緩慢。但現(xiàn)在,美國科學(xué)家或許消滅了這一“攔路虎”,他們將人體多功能干細(xì)胞移植進(jìn)經(jīng)過遺傳改造的豬體內(nèi),不僅沒有出現(xiàn)排斥現(xiàn)象,這些干細(xì)胞還在“新家”茁壯成長。論文發(fā)表在一期的美國《國家科學(xué)院學(xué)報(bào)》上,研究人員表示,成果意味著,我們朝著用干細(xì)胞治療和治愈多種慢性疾病更近了一步。
For Arabidopsis, the sun-induced signaling process involves the binding of an activated photosensitizer (phytochrome) to the transcription factor PIF. This combination will destroy the PIF and shut down its target gene. However, researchers found that phytochromes also punished themselves with the death penalty when PIFs were destroyed, and the immediate implementation of this directive resulted in a weaker signal strength.
"Understanding the dynamics of plant response to light and parsing the underlying molecular mechanisms helps us to genetically engineer crops to better adapt to environmental fluctuations," said co-author of the article, Professor Wang Zhiyong of Carnegie .
Researchers use mutually assured destruction (MAD) to describe this end-all signal-weakening mechanism (MAD was a mutually deterrent cold war strategy). Through this mechanism, nature can escort key functions and it will provide a wide range of enlightenment (from agriculture to cancer research).
The biggest challenge for medical specialists studying the effects of stem cells is that the graft or the cells are often rejected by the subject, slowing down some potentially life-saving therapies. But now, American scientists may eliminate this "stumbling block" by transplanting human pluripotent stem cells into genetically engineered pigs. Not only is there no rejection, these stem cells are still thriving in "new home." The paper, published in the latest issue of the Proceedings of the National Academy of Sciences, said the latest results mean that we are one step closer to treating and curing many chronic diseases with stem cells.