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clearview乙型流感病毒IgM 熒光探針試劑
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clearview乙型流感病毒IgM 熒光探針試劑
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【公司名稱】 廣州健侖生物科技有限公司
【市場(chǎng)部】 楊永漢
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【騰訊 】 2042552662
【公司地址】 廣州清華科技園創(chuàng)新基地番禺石樓鎮(zhèn)創(chuàng)啟路63號(hào)二期2幢101-103室
C型產(chǎn)氣莢膜梭菌可產(chǎn)生α和β兩種毒素,能導(dǎo)致新生犢牛、馬駒、仔豬和羔羊的腸毒血癥,禽的壞死性腸炎,成年綿羊的急性腸毒血癥以及人類的壞死性腸炎等。
按照C型產(chǎn)氣莢膜梭菌感染仔豬后的病程長短,可將其分為:zui急性、急性、亞急性及慢性四種級(jí)別。
zui急性型:癥狀不易觀察,多發(fā)生于出生24 h的仔豬,有些患病仔豬虛弱、后軀沾有血樣稀便,不久就進(jìn)入瀕死狀態(tài),少數(shù)則不表現(xiàn)為任何癥狀就昏倒猝死。
急性型:臨床zui常見,患病豬腹瀉,糞便呈紅褐色,有的有組織碎片,病程一般維持48 h,36 h后死亡。
亞急性型:病程稍慢,癥狀特點(diǎn)為長時(shí)間腹瀉,病初排黃色糞便,之后逐漸變?yōu)楹薪M織碎片的稀便,病程維持5-7 d,zui后死亡。
慢性型:病程比較長,病例為時(shí)好時(shí)壞的間歇腹瀉,排灰黃色糞便,日漸消瘦,zui后常因生長停滯而淘汰,部分死亡。
臨床剖檢時(shí)zui常見癥狀為腸道病變,空腸病理變化zui為嚴(yán)重,腸道內(nèi)容物液化,空腸內(nèi)絨毛脫落壞死,腸系膜及漿膜下有大小不等的小氣泡,腸系膜淋巴結(jié)腫大,多數(shù)呈鮮紅色。病程長的動(dòng)物以壞死性腸炎為主要臨床癥狀,腸粘膜易剝,腸腔內(nèi)含大量壞死組織碎片。
C型產(chǎn)氣莢膜梭菌不僅感染豬,還可感染羊、雞、馬、兔和牛等動(dòng)物。健康動(dòng)物腸道內(nèi)存在該菌,一旦動(dòng)物腸道內(nèi)的菌群失調(diào),產(chǎn)氣莢膜梭菌大量繁殖和生長,排出的糞便污染了動(dòng)物飼料或乳頭。大量的該病菌就會(huì)隨著幼畜吸吮奶或食用污染物等方式進(jìn)入幼畜體內(nèi),侵襲腸絨毛上皮并產(chǎn)生大量毒素,使腸道正常組織破損,毒素趁機(jī)而入,進(jìn)而隨血液循環(huán)侵害其它組織器官。
實(shí)驗(yàn)室中由C型產(chǎn)氣莢膜梭菌所導(dǎo)致的動(dòng)物和人類的腸毒血癥和腸炎,與自然感染的動(dòng)物臨床癥狀相似,病程也可分為亞急性、慢性和急性。其中急性和亞急性病例常表現(xiàn)為精神抑郁、劇烈腹痛和帶血稀便。慢性病例主要發(fā)生在成年動(dòng)物中,其臨床表現(xiàn)為脫水和持續(xù)性腹瀉。炭疽是由炭疽芽孢桿菌引起的烈性自然疫源性人獸共患傳染病。每年人炭疽病例約在2~10萬之間。歐洲、亞洲、非洲、美洲和大洋洲均有該病的發(fā)生。
Clostridium perfringens type C can produce both alpha and beta toxins and can cause enterotoxemia in newborn calves, foals, piglets and lambs, necrotic enteritis in poultry, acute enterotoxemia in adult sheep and Human necrotic enteritis and so on.
According to C-type Clostridium perfringens infected piglets after the course of the disease can be divided into: the most acute, acute, subacute and chronic four levels.
The most acute type: the symptoms are not easy to observe, occurred in piglets born 24 h, some sick piglets weak, stools were stained with blood loose stools, and soon entered a dying condition, a few do not show any symptoms on the sudden death.
Acute type: the most common clinical, sick pigs diarrhea, brown stool, and some tissue fragments, the duration of the general maintenance of 48 h, died after 36 h.
Subacute type: a lesser duration, the symptoms characterized by prolonged diarrhea, the disease early row of yellow droppings, then gradually become loose stools containing tissue fragments, duration of 5-7 d, the last death.
Chronic type: a longer course of illness, the case of intermittent diarrhea, good and bad times, discharge of yellow feces, getting thinner, and finally often due to stagnant growth and out, part of the death.
Clinical examination of the most common symptoms of intestinal disease, pathological changes in the most serious jejunum, intestinal contents of liquefaction, jejunum villi off necrosis, mesenteric and subserosal size of small bubbles, mesenteric lymph nodes, most were Red. Long duration of the disease to necrotizing enterocolitis as the main clinical symptoms, intestinal mucosa easy to peel, the intestine contains a large number of necrotic tissue fragments.
Clostridium perfringens type C not only infect pigs, but also in sheep, chickens, horses, rabbits and cattle and other animals. The bacteria present in the intestine of healthy animals, and Clostridium perfringens multiplies and grows once the flora in the intestine of the animal is out of control. The excreted feces contaminate the animal feed or the nipple. A large number of the bacteria will be with young animals suck milk or food contaminants into the young animals such as the body, invasion of intestinal villi and produce large amounts of toxins, the normal tissue damage to the intestine, toxin took the opportunity to enter, and then infringement of blood circulation with other Tissue organs.
Animal and human enterotoxemia and enteritis caused by C-type Clostridium perfringens in laboratory are similar to the clinical symptoms of naturally infected animals. The course of the disease can be divided into subacute, chronic and acute. The acute and subacute cases often show depression, severe abdominal pain and loose stools. Chronic cases occur mainly in adult animals, with clinical manifestations of dehydration and persistent diarrhea. Anthrax is a potent natural foci of zoonosis caused by Bacillus anthracis. Anthrax cases worldwide each year about 2 to 10 million. The disease occurs in Europe, Asia, Africa, the Americas and Oceania.